Re-emergence of fatal human influenza A subtype H5N1 disease
نویسندگان
چکیده
منابع مشابه
Influenza A Strain-Dependent Pathogenesis in Fatal H1N1 and H5N1 Subtype Infections of Mice
To determine if fatal infections caused by different highly virulent influenza A viruses share the same pathogenesis, we compared 2 different influenza A virus subtypes, H1N1 and H5N1. The subtypes, which had shown no pathogenicity in laboratory mice, were forced to evolve by serial passaging. Although both adapted viruses evoked diffuse alveolar damage and showed a similar 50% mouse lethal dos...
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In 2014, novel highly pathogenic avian influenza A H5N2, H5N5, H5N6, and H5N8 viruses caused outbreaks in Asia, Europe, and North America. The H5 genes of these viruses form a monophyletic group that evolved from a clade 2.3.4 H5N1 variant. This rapid emergence of new H5Nx combinations is unprecedented in the H5N1 evolutionary history.
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positive samples have been identifi ed during outbreaks. Molecular methods may serve as an adjunct to traditional laboratory methods by improving sensitivity and also enabling diagnosis of Shigella spp. outbreaks among remote populations where specimen storage and transport requirements may be challenging (10). We describe extremely high rates of resistance of Shigella spp. to cotrimoxazole, th...
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BACKGROUND Oseltamivir is widely used as treatment for influenza virus A subtype H5N1 (hereafter, "H5N1") infection but, like any intervention, is not always effective. METHODS We used Avian Influenza Registry data from 10 countries to examine the risk of death in 215 patients with confirmed H5N1 infection who were treated with oseltamivir, according to viral clade, age, respiratory failure, ...
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H pathogenic avian influenza (HPAI) H5N1 has spread across Asia, Europe, and Africa. Not limited to poultry, the virus has also been shown to cross the species barrier infecting humans (1) and felines, including domestic cats (2) and tigers (3–5). Both cats and tigers were reported as becoming infected after eating poultry carcasses harboring HPAI. Here, we report a case of HPAI H5N1 infection ...
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ژورنال
عنوان ژورنال: The Lancet
سال: 2004
ISSN: 0140-6736
DOI: 10.1016/s0140-6736(04)15595-5